CVSS 3.1
9.3 criticalCVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:C/C:N/I:H/A:LCVE-2026-48705
Critical (9.3) in project-monai monai. EPSS 0.5% estimated probability of exploitation activity in the next 30 days. Fixed in monai 1.6.1.
On this page
MONAI (Medical Open Network for AI) is an AI toolkit for health care imaging. Prior to 1.6.1, PydicomReader._get_affine() trusts non-finite values in the DICOM PixelSpacing, ImagePositionPatient, and ImageOrientationPatient fields and composes them into an affine matrix without validation. An unauthenticated attacker who can upload a crafted DICOM to a default MONAILabel deployment can propagate NaN or infinity values through LoadImaged, Spacingd, model inference, and output writing, causing inference failures, persistent datastore poisoning, or geometrically corrupted results. This issue is fixed in version 1.6.1.
Severity
- EPSS
- 0.5% estimated probability of exploitation activity in the next 30 days; 44th percentile. Scored 2026-11-10. A forecast for this CVE across the internet, not for your own systems.
- CISA's assessment (SSVC)
- Exploitation: PoC · Automatable: yes · Technical impact: partial, assessed 2026-11-05. From CISA's Vulnrichment in the CVE List: whether it is exploited, whether exploiting it can be automated, and how much control it gives.
- OWASP Top 10
- A05:2025 Injection
- Published
- Modified
- NVD analysis
- Deferred: the NVD does not plan to analyze it
- Record from
- the NVD, synced
Ask an AI about this CVE
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Explain CVE-2026-48705 for an engineer deciding whether to act. Use https://cve.bz/api/public/cves/CVE-2026-48705?via=ask-ai-copy and https://cve.bz/cve/CVE-2026-48705?via=ask-ai-copy as the source of truth: what is affected and which versions fix it, whether it is in CISA KEV, public exploits, and its EPSS (an internet-wide 30-day estimate of exploitation activity, not a forecast for my systems). If they give no fixed versions, use the CVE record https://cveawg.mitre.org/api/cve/CVE-2026-48705 or the vendor advisory, not third-party mirrors. Tell me how to check whether I am affected and how to verify a fix. Cite the sources and say where they are uncertain.Opens a third-party assistant; its answer is its own, not cve.bz's. The prompt holds only this CVE's id and public links.
Affected
Versions
From the CNA's record in the CVE List.
| Product | Affected |
|---|---|
| Project-MONAI MONAI | < 1.6.1 |
Packages (OSV)
| Advisory | Ecosystem | Package | Affected | Fixed in |
|---|---|---|---|---|
| GHSA-6hp3-vr39-rqw8 | PyPI | monai | <1.6.1 | 1.6.1 |
Attack patterns (CAPEC)
The attack patterns MITRE's CAPEC relates to this record's weaknesses, as MITRE names them. Credits. More on the page of CWE-20 (51).