{"cve":"CVE-2025-50675","nvd":{"published":"2025-08-07T19:15:28.597","modified":"2026-06-17T09:35:18.120","status":"Deferred","description":"GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation.","cvss_v4":null,"cvss_v3":{"version":"3.1","vector":"CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H","score":7.8},"cwes":["CWE-732"],"references":["https://github.com/LukeSec/CVE-2025-50675-GPMAW-Permissions/tree/main","https://www.gpmaw.com/html/downloads.html","https://github.com/LukeSec/CVE-2025-50675-GPMAW-Permissions/tree/main"],"products":[],"source":"nvd","synced_at":"2026-10-19T22:06:45.861874017+00:00"},"epss":{"cve":"CVE-2025-50675","score":0.00246,"percentile":0.15909,"date":"2026-10-31"},"kev":null,"osv":[],"attribution":["This product uses the NVD API but is not endorsed or certified by the NVD.","EPSS scores: FIRST Exploit Prediction Scoring System, https://www.first.org/epss","Known exploited vulnerabilities: CISA Known Exploited Vulnerabilities Catalog, https://www.cisa.gov/known-exploited-vulnerabilities-catalog","Package advisories: OSV (https://osv.dev), from the GitHub Advisory Database, PyPA, Go, RustSec and other ecosystem databases, under CC-BY 4.0 or CC0","CVE records: the CVE Program's CVE List (https://www.cve.org), under its terms of use (https://www.cve.org/Legal/TermsOfUse). CVE is a registered trademark of The MITRE Corporation; this product is not affiliated with the CVE Program."]}