{"cve":"CVE-2024-50636","nvd":{"published":"2024-11-11T23:15:05.833","modified":"2026-06-17T08:04:51.253","status":"Deferred","description":"PyMOL 2.5.0 contains a vulnerability in its \"Run Script\" function, which allows the execution of arbitrary Python code embedded within .PYM files. Attackers can craft a malicious .PYM file containing a Python reverse shell payload and exploit the function to achieve Remote Command Execution (RCE). This vulnerability arises because PyMOL treats .PYM files as Python scripts without properly validating or restricting the commands within the script, enabling attackers to run unauthorized commands in the context of the user running the application.","cvss_v4":null,"cvss_v3":{"version":"3.1","vector":"CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H","score":9.8},"cwes":["CWE-94"],"references":["https://github.com/schrodinger/pymol-open-source/issues/405","https://github.com/yamerooo123/CVE/blob/main/CVE-2024-50636/Description.md","https://youtu.be/SWnN_a1tUNc"],"products":[],"source":"nvd","synced_at":"2026-10-19T21:57:07.693694550+00:00"},"epss":{"cve":"CVE-2024-50636","score":0.01246,"percentile":0.69324,"date":"2026-11-01"},"kev":null,"osv":[],"attribution":["This product uses the NVD API but is not endorsed or certified by the NVD.","EPSS scores: FIRST Exploit Prediction Scoring System, https://www.first.org/epss","Known exploited vulnerabilities: CISA Known Exploited Vulnerabilities Catalog, https://www.cisa.gov/known-exploited-vulnerabilities-catalog","Package advisories: OSV (https://osv.dev), from the GitHub Advisory Database, PyPA, Go, RustSec and other ecosystem databases, under CC-BY 4.0 or CC0","CVE records: the CVE Program's CVE List (https://www.cve.org), under its terms of use (https://www.cve.org/Legal/TermsOfUse). CVE is a registered trademark of The MITRE Corporation; this product is not affiliated with the CVE Program."]}